1/2/2023 0 Comments Honey select update notesThis type of bacterial resistance to the antimicrobial agents poses a very serious threat to public health, and for all kinds of antibiotics, including the major last-resort drugs, the frequencies of resistance are increasing worldwide. However, as resistant pathogens develop and spread, the effectiveness of the antibiotics is diminished. Thus, identification and characterization of the active principle(s) may provide valuable information on the quality and possible therapeutic potential of honeys (against several health disorders of humans), and hence we discussed the medicinal property of honeys with emphasis on their antibacterial activities.Īntimicrobial agents are essentially important in reducing the global burden of infectious diseases. But, there is a large variation in the antimicrobial activity of some natural honeys, which is due to spatial and temporal variation in sources of nectar. The medical grade honeys have potent in vitro bactericidal activity against antibiotic-resistant bacteria causing several life-threatening infections to humans. Its mechanism may be related to the low pH level of honey and its high sugar content (high osmolarity) that is enough to hinder the growth of microbes. However, another kind of honey, called non-peroxide honey ( viz., manuka honey), displays significant antibacterial effects even when the hydrogen peroxide activity is blocked. The antimicrobial activity in most honeys is due to the enzymatic production of hydrogen peroxide. Its immunomodulatory property is relevant to wound repair too. The healing property of honey is due to the fact that it offers antibacterial activity, maintains a moist wound condition, and its high viscosity helps to provide a protective barrier to prevent infection. Indeed, medicinal importance of honey has been documented in the world's oldest medical literatures, and since the ancient times, it has been known to possess antimicrobial property as well as wound-healing activity.
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